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dc.contributor.authorRuiz Alonso, Sandra
dc.contributor.authorVillate Beitia, Ane Ilia
dc.contributor.authorGallego Garrido, Idoia
dc.contributor.authorLafuente Merchán, Markel
dc.contributor.authorPuras Ochoa, Gustavo
dc.contributor.authorSáenz del Burgo Martínez, Laura ORCID
dc.contributor.authorPedraz Muñoz, José Luis ORCID
dc.date.accessioned2021-04-13T08:40:33Z
dc.date.available2021-04-13T08:40:33Z
dc.date.issued2021-02-26
dc.identifier.citationPharmaceutics 13(3) : (2021) // Article ID 308es_ES
dc.identifier.issn1999-4923
dc.identifier.urihttp://hdl.handle.net/10810/50898
dc.description.abstractThree-dimensional (3D) printing is a game changer technology that holds great promise for a wide variety of biomedical applications, including ophthalmology. Through this emerging technique, specific eye tissues can be custom-fabricated in a flexible and automated way, incorporating different cell types and biomaterials in precise anatomical 3D geometries. However, and despite the great progress and possibilities generated in recent years, there are still challenges to overcome that jeopardize its clinical application in regular practice. The main goal of this review is to provide an in-depth understanding of the current status and implementation of 3D bioprinting technology in the ophthalmology field in order to manufacture relevant tissues such as cornea, retina and conjunctiva. Special attention is paid to the description of the most commonly employed bioprinting methods, and the most relevant eye tissue engineering studies performed by 3D bioprinting technology at preclinical level. In addition, other relevant issues related to use of 3D bioprinting for ocular drug delivery, as well as both ethical and regulatory aspects, are analyzed. Through this review, we aim to raise awareness among the research community and report recent advances and future directions in order to apply this advanced therapy in the eye tissue regeneration field.es_ES
dc.description.sponsorshipThis research was fundedby the Basque Country Government (Department of Education, University and Research, Consolidated Groups IT907-16 and grant number PRE_2020_2_0143), and forms part of the Nanogrow project RTC-2017-6696-1. Additional funding was provided by the CIBER of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), and initiative of the Carlos III Health Institute (ISCIII) and by the University of the Basque Country (UPV/EHU), post-doctoral grant number ESPDOC19/47). The APC was funded by the Basque Country Government (Department of Education, University and Research, Consolidated Groups IT907-16).es_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/
dc.subject3D bioprintinges_ES
dc.subjectcorneaes_ES
dc.subjectretinaes_ES
dc.subjectophthalmologyes_ES
dc.subjecttissue regenerationes_ES
dc.titleCurrent Insights into 3D Bioprinting: An Advanced Approach for Eye Tissue Regenerationes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.date.updated2021-03-26T14:08:08Z
dc.rights.holder2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).es_ES
dc.relation.publisherversionhttps://www.mdpi.com/1999-4923/13/3/308/htmes_ES
dc.identifier.doi10.3390/pharmaceutics13030308
dc.departamentoesFarmacia y ciencias de los alimentos
dc.departamentoeuFarmazia eta elikagaien zientziak


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2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Except where otherwise noted, this item's license is described as 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).