Association between long term exposure to particulate matter and incident hypertension in Spain
dc.contributor.author | Doulatram Gamgaram, Viyey | |
dc.contributor.author | Valdés, Sergio | |
dc.contributor.author | Maldonado Araque, Cristina | |
dc.contributor.author | Lago Sampedro, Ana | |
dc.contributor.author | Badía Guillén, Rocío | |
dc.contributor.author | García Escobar, Eva | |
dc.contributor.author | García Serrano, Sara | |
dc.contributor.author | García Vivanco, Marta | |
dc.contributor.author | Garrido, Juan Luis | |
dc.contributor.author | Theobald, Mark Richard | |
dc.contributor.author | Gil, Victoria | |
dc.contributor.author | Martín Llorente, Fernando | |
dc.contributor.author | Calle Pascual, Alfonso | |
dc.contributor.author | Bordiú, Elena | |
dc.contributor.author | Castaño González, Luis Antonio | |
dc.contributor.author | Delgado, Elías | |
dc.contributor.author | Franch Nadal, Josep | |
dc.contributor.author | Chaves, Felipe J. | |
dc.contributor.author | Montanya, Eduard | |
dc.contributor.author | Galán García, José Luis | |
dc.contributor.author | Aguilera Venegas, Gabriel | |
dc.contributor.author | Soriguer, Federico | |
dc.contributor.author | Rojo Martínez, Gemma | |
dc.date.accessioned | 2021-11-26T09:48:43Z | |
dc.date.available | 2021-11-26T09:48:43Z | |
dc.date.issued | 2021-10-05 | |
dc.identifier.citation | Scientific Reports 11(1) : (2021) // Article ID 19702 | es_ES |
dc.identifier.issn | 2045-2322 | |
dc.identifier.uri | http://hdl.handle.net/10810/54121 | |
dc.description.abstract | [EN]Exposure to air particulate matter has been linked with hypertension and blood pressure levels. The metabolic risks of air pollution could vary according to the specific characteristics of each area, and has not been sufficiently evaluated in Spain. We analyzed 1103 individuals, participants in a Spanish nationwide population based cohort study (di@bet.es), who were free of hypertension at baseline (2008-2010) and completed a follow-up exam of the cohort (2016-2017). Cohort participants were assigned air pollution concentrations for particulate matter < 10 mu m (PM10) and < 2.5 mu m (PM2.5) during follow-up (2008-2016) obtained through modeling combined with measurements taken at air quality stations (CHIMERE chemistry-transport model). Mean and SD concentrations of PM10 and PM2.5 were 20.17 +/- 3.91 mu g/m(3) and 10.83 +/- 2.08 mu g/m(3) respectively. During follow-up 282 cases of incident hypertension were recorded. In the fully adjusted model, compared with the lowest quartile of PM10, the multivariate weighted ORs (95% CIs) for developing hypertension with increasing PM10 exposures were 0.82 (0.59-1.14), 1.28 (0.93-1.78) and 1.45 (1.05-2.01) in quartile 2, 3 and 4 respectively (p for a trend of 0.003). The corresponding weighted ORs according to PM2.5 exposures were 0.80 (0.57-1.13), 1.11 (0.80-1.53) and 1.48 (1.09-2.00) (p for trend 0.004). For each 5-mu g/m(3) increment in PM10 and PM2.5 concentrations, the odds for incident hypertension increased 1.22 (1.06-1.41) p = 0.007 and 1.39 (1.07-1.81) p = 0.02 respectively. In conclusion, our study contributes to assessing the impact of particulate pollution on the incidence of hypertension in Spain, reinforcing the need for improving air quality as much as possible in order to decrease the risk of cardiometabolic disease in the population. | es_ES |
dc.description.sponsorship | CIBERDEM (Ministerio de Economia, Industria y Competitividad-ISCIII), Ministerio de Sanidad, Servicios Sociales e Igualdad-ISCIII, Instituto de Salud Carlos III (PI17/02136, PI20/01322), European Regional Development Fund (ERDF) "A way to build Europe". Ayudas a la investigacion SED 2020. GRM belongs to the regional Nicolas Monardes research program of the Consejeria de Salud (C-0060-2012 and RC-0006-2016; Junta de Andalucia, Spain). CMA is recipient of a "Rio Hortega" research contract (CM19/00186, Instituto de Salud Carlos III). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Nature Research | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.subject | self-reported hypertension | es_ES |
dc.subject | ambient air-pollution | es_ES |
dc.subject | blood-pressure | es_ES |
dc.subject | cardiovascular-disease | es_ES |
dc.subject | traffic noise | es_ES |
dc.subject | benefits | es_ES |
dc.subject | cohorts | es_ES |
dc.subject | fine | es_ES |
dc.title | Association between long term exposure to particulate matter and incident hypertension in Spain | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | © The Author(s) 2021. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http:// creat iveco mmons. org/ licen ses/ by/4. 0/ | es_ES |
dc.rights.holder | Atribución 3.0 España | * |
dc.relation.publisherversion | https://www.nature.com/articles/s41598-021-99154-7 | es_ES |
dc.identifier.doi | 10.1038/s41598-021-99154-7 | |
dc.departamentoes | Pediatría | es_ES |
dc.departamentoeu | Pediatria | es_ES |
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