Oral Pemphigoid Recalcitrant Lesion Treated with PRGF Infiltration. Case Report
dc.contributor.author | Anitua Aldekoa, Eduardo | |
dc.contributor.author | Alkhraisat, Mohammad Hamdan | |
dc.contributor.author | Eguía del Valle, Asier | |
dc.contributor.author | Piñas, Laura | |
dc.date.accessioned | 2021-11-29T11:54:31Z | |
dc.date.available | 2021-11-29T11:54:31Z | |
dc.date.issued | 2021-11-19 | |
dc.identifier.citation | Dentistry Journal 9(11) : (2021) // Article ID 137 | es_ES |
dc.identifier.issn | 2304-6767 | |
dc.identifier.uri | http://hdl.handle.net/10810/54170 | |
dc.description.abstract | Mucous membrane pemphigoid (MMP) is a heterogeneous group of chronic autoimmune subepithelial blistering diseases. Oral involvement is present in almost all patients, may represent the onset of the disease, and causes different degrees of pain, dysphagia, soreness, and bleeding. Treatment is based on systemic and/or oral corticoids, or other immunosuppressants. Occasionally, oral lesions can show a poor response to standard treatments. We present the case of a 61-year-old female patient with a painful extensive MMP oral ulcerative lesion recalcitrant to previous systemic azathioprine and local triamcinolone treatment, which was successfully treated in a novel way using PRGF infiltrations as adjuvant. After four weekly infiltrations, pain was reduced from 10 to 0 in a VAS and the lesion was completely healed. The patient continued with a low dose maintenance immunosuppressive treatment (prednisone 5 mg/day PO), and after 13 months of follow-up, there was no relapse of the lesion and no side effects. Although future research is necessary to confirm these observations, PRGF could be a useful adjuvant for the management of extensive mucous membrane pemphigoid oral lesions. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | |
dc.subject | benign mucous membrane pemphigoid | es_ES |
dc.subject | autoimmune disease | es_ES |
dc.subject | vesiculobullous dermatoses | es_ES |
dc.subject | platelet rich plasma | es_ES |
dc.subject | case report | es_ES |
dc.title | Oral Pemphigoid Recalcitrant Lesion Treated with PRGF Infiltration. Case Report | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.date.updated | 2021-11-25T15:59:52Z | |
dc.rights.holder | 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). | es_ES |
dc.relation.publisherversion | https://www.mdpi.com/2304-6767/9/11/137/htm | es_ES |
dc.identifier.doi | 10.3390/dj9110137 | |
dc.departamentoes | Estomatología II | |
dc.departamentoeu | Estomatologia II |
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Except where otherwise noted, this item's license is described as 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).