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Diethyl(benzamido(diisopropoxyphosphoryl)methyl) phosphonate

dc.contributor.authorLópez Francés, Adrián ORCID
dc.contributor.authorPalacios Gambra, Francisco Javier ORCID
dc.contributor.authorMaestro Burzaco, Aitor
dc.contributor.authorVicario Hernando, Javier ORCID
dc.date.accessioned2022-09-30T12:23:59Z
dc.date.available2022-09-30T12:23:59Z
dc.date.issued2022-08-11
dc.identifier.citationMolbank 2022(3) : (2022) // Article ID M1424es_ES
dc.identifier.issn1422-8599
dc.identifier.urihttp://hdl.handle.net/10810/57881
dc.description.abstractBisphosphonates are widely used in medicine and related areas, mainly for the treatment of bone diseases, such as osteoporosis. However, their synthesis is usually performed under harsh reaction conditions. In order to overcome this limitation, the present work illustrates a new synthetic route to access the title α-aminobisphosphonate in milder reaction conditions using α-phosphorylated imines as key intermediates.es_ES
dc.description.sponsorshipFinancial support by Ministerio de Economía, Industria y Competividad (RTI2018-101818-B-I00) and Gobierno Vasco (GV, IT 992-16) is gratefully acknowledged. A.L.-F. thanks the Basque Country Government for a predoctoral grant.es_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.relationinfo:eu-repo/grantAgreement/MICIU/RTI2018-101818-B-I00es_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectbisphosphonateses_ES
dc.subjectα-iminophosphonateses_ES
dc.subjectPudovik reactiones_ES
dc.titleDiethyl(benzamido(diisopropoxyphosphoryl)methyl) phosphonatees_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.date.updated2022-09-22T12:03:24Z
dc.rights.holder© 2022 by the authors.Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/ 4.0/).es_ES
dc.relation.publisherversionhttps://www.mdpi.com/1422-8599/2022/3/M1424es_ES
dc.identifier.doi10.3390/M1424
dc.departamentoesQuímica orgánica I
dc.departamentoeuKimika organikoa I


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© 2022 by the authors.Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/ 4.0/).
Except where otherwise noted, this item's license is described as © 2022 by the authors.Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/ 4.0/).