Molecularly Imprinted Polymer-Based Sensors for the Detection of Skeletal- and Cardiac-Muscle-Related Analytes
dc.contributor.author | Ostrovidov, Serge | |
dc.contributor.author | Ramalingam, Murugan | |
dc.contributor.author | Bae, Hojae | |
dc.contributor.author | Orive Arroyo, Gorka | |
dc.contributor.author | Fujie, Toshinori | |
dc.contributor.author | Hori, Takeshi | |
dc.contributor.author | Nashimoto, Yuji | |
dc.contributor.author | Shi, Xuetao | |
dc.contributor.author | Kaji, Hirokazu | |
dc.date.accessioned | 2023-08-09T07:45:16Z | |
dc.date.available | 2023-08-09T07:45:16Z | |
dc.date.issued | 2023-06-15 | |
dc.identifier.citation | Sensors 23(12) : (2023) // Article ID 5625 | es_ES |
dc.identifier.issn | 1424-8220 | |
dc.identifier.uri | http://hdl.handle.net/10810/62139 | |
dc.description.abstract | Molecularly imprinted polymers (MIPs) are synthetic polymers with specific binding sites that present high affinity and spatial and chemical complementarities to a targeted analyte. They mimic the molecular recognition seen naturally in the antibody/antigen complementarity. Because of their specificity, MIPs can be included in sensors as a recognition element coupled to a transducer part that converts the interaction of MIP/analyte into a quantifiable signal. Such sensors have important applications in the biomedical field in diagnosis and drug discovery, and are a necessary complement of tissue engineering for analyzing the functionalities of the engineered tissues. Therefore, in this review, we provide an overview of MIP sensors that have been used for the detection of skeletal- and cardiac-muscle-related analytes. We organized this review by targeted analytes in alphabetical order. Thus, after an introduction to the fabrication of MIPs, we highlight different types of MIP sensors with an emphasis on recent works and show their great diversity, their fabrication, their linear range for a given analyte, their limit of detection (LOD), specificity, and reproducibility. We conclude the review with future developments and perspectives. | es_ES |
dc.description.sponsorship | This work was supported in part by the Japan Society for the Promotion of Science (JSPS) KAKENHI (Grant Numbers 22K18936, and 23H01821), and the Research Center for Biomedical Engineering at Tokyo Medical and Dental University, Japan. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.subject | molecularly imprinted polymers (MIP) | es_ES |
dc.subject | biomaterials | es_ES |
dc.subject | sensors | es_ES |
dc.subject | skeletal muscle | es_ES |
dc.subject | cardiac muscle | es_ES |
dc.title | Molecularly Imprinted Polymer-Based Sensors for the Detection of Skeletal- and Cardiac-Muscle-Related Analytes | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.date.updated | 2023-06-27T13:22:22Z | |
dc.rights.holder | © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/ 4.0/). | es_ES |
dc.relation.publisherversion | https://www.mdpi.com/1424-8220/23/12/5625 | es_ES |
dc.identifier.doi | 10.3390/s23125625 | |
dc.departamentoes | Farmacia y ciencias de los alimentos | |
dc.departamentoeu | Farmazia eta elikagaien zientziak |
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Except where otherwise noted, this item's license is described as © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/ 4.0/).