Show simple item record

dc.contributor.authorCarral Menoyo, Asier
dc.contributor.authorSotorríos Manrique, Lia
dc.contributor.authorOrtiz de Elguea Flecha, Verónica
dc.contributor.authorDíaz Andrés, Aitor
dc.contributor.authorSotomayor Anduiza, María Nuria
dc.contributor.authorGómez Bengoa, Enrique
dc.contributor.authorLete Expósito, María Esther
dc.date.accessioned2023-11-22T13:21:03Z
dc.date.available2023-11-22T13:21:03Z
dc.date.issued2019-12-30
dc.identifier.citationThe Journal of Organic Chemistry 85(4) : 2486-2503(2020)es_ES
dc.identifier.issn1520-6904
dc.identifier.issn0022-3263
dc.identifier.urihttp://hdl.handle.net/10810/63117
dc.description.abstractA protocol for the Pd(II)-catalyzed C-H alkenylation reaction of substituted N-allylanilines via an unusual 6-endo process has been developed. A DFT study of the mechanistic pathway has shown that the coordination of the remote protecting group to the palladium center is determinant for the control of the regioselectivity in favor of the 6-endo process. The reaction would proceed via prior activation of the alkene. This procedure constitutes a mild and efficient method for the synthesis of 1,4- dihydroquinoline derivatives from simple and readily accessible substrates.es_ES
dc.description.sponsorshipMinisterio de Economía y Competitividad (CTQ2016-74881-P; CTQ2016-78083-P) // Gobierno Vasco (IT1045-16)es_ES
dc.language.isoenges_ES
dc.publisherAmerican Chemical Societyes_ES
dc.relationinfo:eu-repo/grantAgreement/MINECO/CTQ2016-74881-Pes_ES
dc.relationinfo:eu-repo/grantAgreement/MINECO/CTQ2016-78083-Pes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.subjectpalladiumes_ES
dc.subjectC-H alkenylationes_ES
dc.subjectquinolineses_ES
dc.subjectDFT calculationses_ES
dc.subjectcyclizationes_ES
dc.titleIntramolecular Palladium(II)-catalyzed 6-endo C-H alkenylation directed by the remote N-protecting group. Mechanistic insight and application to the synthesis of dihydroquinolineses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.holder© 2019, American Chemical Societyes_ES
dc.relation.publisherversionhttps://pubs.acs.org/doi/10.1021/acs.joc.9b03174es_ES
dc.relation.publisherversionhttps://doi.org/10.1021/acs.joc.9b03174es_ES
dc.identifier.doi10.1021/acs.joc.9b03174
dc.departamentoesQuímica orgánica IIes_ES
dc.departamentoeuKimika organikoa IIes_ES


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record