Gold Nanoclusters Synthesized within Single-Chain Nanoparticles as Catalytic Nanoreactors in Water
dc.contributor.author | Pinacho Olaciregui, Jokin | |
dc.contributor.author | Verde Sesto, Ester | |
dc.contributor.author | Taton, Daniel | |
dc.contributor.author | Pomposo Alonso, José Adolfo ![]() | |
dc.date.accessioned | 2024-04-09T16:46:47Z | |
dc.date.available | 2024-04-09T16:46:47Z | |
dc.date.issued | 2024-01-30 | |
dc.identifier.citation | Polymers 16(3) : (2024) // Article ID 378 | es_ES |
dc.identifier.issn | 2073-4360 | |
dc.identifier.uri | http://hdl.handle.net/10810/66579 | |
dc.description.abstract | Metalloenzymes are able to catalyze complex biochemical reactions in cellular (aqueous) media with high efficiency. In recent years, a variety of metal-containing single-chain nanoparticles (SCNPs) have been synthesized as simplified metalloenzyme-mimetic nano-objects. However, most of the metal-containing SCNPs reported so far contained complexed metal ions but not metal nanoclusters (NCs) with diameter <5 nm, which could be used as powerful, emerging catalysts. Herein, we report the synthesis of gold nanoclusters (Au-NCs) within SCNPs and the further use of Au-NCs/SCNPs as catalytic nanoreactors in water. We demonstrate that a common motif contained in several drugs (i.e., the aminophenyl–oxazolidinone fragment present in Rivaroxaban, Sutezolid, and Linezolid) can be efficiently prepared in water from a hydrophobic precursor compound by using the Au-NCs/SCNPs as efficient catalytic nanoreactors. In summary, this work paves the way forthe synthesis of metal–NCs/SCNPs for advanced catalysis in aqueous media. | es_ES |
dc.description.sponsorship | We gratefully acknowledge Grant PID2021-123438NB-I00 funded by MCIN/AEI/10.13039/501100011033 and “ERDF A way of making Europe”, Grant TED2021-130107A-I00 funded by MCIN/AEI/10.13039/501100011033 and Unión Europea “NextGenerationEU/PRTR”, and Grant IT-1566-22 from Eusko Jaurlaritza (Basque Government). J. P.-O. acknowledges a predoctoral contract for the completion of his PhD thesis under joint supervision between the University of the Basque Country (UPV/EHU) and the University of Bordeaux (UB). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.relation | info:eu-repo/grantAgreement/MICINN/PID2021-123438NB-I00 | es_ES |
dc.relation | info:eu-repo/grantAgreement/MICINN/TED2021-130107A-I00 | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/es/ | |
dc.subject | single-chain nanoparticles | es_ES |
dc.subject | gold nanoclusters | es_ES |
dc.subject | catalytic nanoreactors | es_ES |
dc.title | Gold Nanoclusters Synthesized within Single-Chain Nanoparticles as Catalytic Nanoreactors in Water | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.date.updated | 2024-02-09T15:07:02Z | |
dc.rights.holder | © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/ 4.0/). | es_ES |
dc.relation.publisherversion | https://www.mdpi.com/2073-4360/16/3/378 | es_ES |
dc.identifier.doi | 10.3390/polym16030378 | |
dc.departamentoes | Polímeros y Materiales Avanzados: Física, Química y Tecnología | |
dc.departamentoeu | Polimero eta Material Aurreratuak: Fisika, Kimika eta Teknologia |
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Except where otherwise noted, this item's license is described as © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/ 4.0/).