dc.contributor.author | Baztarrika, Itsaso | |
dc.contributor.author | Salazar Sánchez, Adrián | |
dc.contributor.author | Laorden Muñoz, Lorena | |
dc.contributor.author | Martínez Ballesteros, Ilargi | |
dc.contributor.author | Alonso Monsalve, Rodrigo | |
dc.contributor.author | Martínez Malax-Echevarría, Irati | |
dc.date.accessioned | 2024-04-22T17:22:37Z | |
dc.date.available | 2024-04-22T17:22:37Z | |
dc.date.issued | 2024-04 | |
dc.identifier.citation | Food Microbiology 118 : (2024) // Article ID 104424 | es_ES |
dc.identifier.issn | 0740-0020 | |
dc.identifier.issn | 1095-9998 | |
dc.identifier.uri | http://hdl.handle.net/10810/66854 | |
dc.description.abstract | Infection mechanisms of Arcobacter remain uncertain. This study aimed to determine whether 65 food and waterborne isolates of at least six species were able to adhere and invade Caco-2 cells; and whether this ability could be related to cadF, cj1349, ciaB, and/or hecA, specific genetic markers related to host cell adhesion and invasion. All adhered and invaded the cells, and harboured at least two virulence markers. The mean virulent activity shown by A. butzleri was superior to that of A. cryaerophilus (p < 0.05); but the mean adhesion and invasion values of A. lanthieri, A. skirrowii, and A. vitoriensis were even higher. Sewage isolates were significantly (p < 0.05) more adherent and invasive than the rest, and their associated gene content was higher (p < 0.05). For the first time, an association between cadF and hecA and a high adhesion capability was identified (p < 0.05). The results provide new data on the pathogenic potential of Arcobacter species present in food and water by highlighting the superiority of A. butzleri over A. cryarophilus; providing evidence on the virulence of minority species as A. lanthieri and A. vitoriensis; and confirming sewage as an important source of potentially more virulent arcobacters. | es_ES |
dc.description.sponsorship | This work was supported by the Spanish Ministry of Economy and Competitiveness [grant number AGL2014-56179-P, co-financed with FEDER funds]; Basque Government [grant number PA20/03]; and the University of the Basque Country UPV/EHU [grant number GIU21/021]. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.relation | info:eu-repo/grantAgreement/MINECO/AGL2014-56179-P | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.subject | Arcobacter spp. | es_ES |
dc.subject | foodstuff | es_ES |
dc.subject | river water | es_ES |
dc.subject | sewage | es_ES |
dc.subject | caco-2 infection | es_ES |
dc.subject | PCR | es_ES |
dc.title | Foodborne and waterborne Arcobacter species exhibit a high virulent activity in Caco-2 | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | © 2023 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-
nc-nd/4.0/). | es_ES |
dc.rights.holder | Atribución-NoComercial-SinDerivadas 3.0 España | * |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S0740002023002113 | es_ES |
dc.identifier.doi | 10.1016/j.fm.2023.104424 | |
dc.departamentoes | Inmunología, microbiología y parasitología | es_ES |
dc.departamentoeu | Immunologia, mikrobiologia eta parasitologia | es_ES |