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dc.contributor.authorMaeso, Lidia
dc.contributor.authorAntezana, Pablo Edmundo
dc.contributor.authorHvozda Arana, Ailen Gala
dc.contributor.authorEvelson, Pablo Andrés
dc.contributor.authorOrive Arroyo, Gorka
dc.contributor.authorDesimone, Martin Federico
dc.date.accessioned2024-05-08T15:58:02Z
dc.date.available2024-05-08T15:58:02Z
dc.date.issued2024-04-10
dc.identifier.citationPharmaceutics 16(4) : (2024) // Article ID 524es_ES
dc.identifier.issn1999-4923
dc.identifier.urihttp://hdl.handle.net/10810/67764
dc.description.abstractThe skin is the largest organ of the body, and it acts as a protective barrier against external factors. Chronic wounds affect millions of people worldwide and are associated with significant morbidity and reduced quality of life. One of the main factors involved in delayed wound healing is oxidative injury, which is triggered by the overproduction of reactive oxygen species. Oxidative stress has been implicated in the pathogenesis of chronic wounds, where it is known to impair wound healing by causing damage to cellular components, delaying the inflammatory phase of healing, and inhibiting the formation of new blood vessels. Thereby, the treatment of chronic wounds requires a multidisciplinary approach that addresses the underlying causes of the wound, provides optimal wound care, and promotes wound healing. Among the promising approaches to taking care of chronic wounds, antioxidants are gaining interest since they offer multiple benefits related to skin health. Therefore, in this review, we will highlight the latest advances in the use of natural polymers with antioxidants to generate tissue regeneration microenvironments for skin wound healing.es_ES
dc.description.sponsorshipThis work was assisted by the Spanish Ministry of Economy, Industry, and Competitiveness (PID2022-139746OB-I00/AEI/10.13039/501100011033) and received technical support from the ICTS NANBIOSIS (Drug Formulation Unit, U10) at the University of the Basque Country. Maeso L also thanks the Basque Government for awarding the Ph.D. grant (PRE_2022_1_0053). The authors would like to acknowledge grants from the Universidad de Buenos Aires, UBACYT 20020150100056BA and PIDAE 2022 (Martín F. Desimone), and from CONICET PIP 0826 (Martín F. Desimone).es_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.relationinfo:eu-repo/grantAgreement/MICINN/PID2021-123146OB-I00es_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/es/
dc.subjectbiomaterialses_ES
dc.subjectantioxidantses_ES
dc.subjectwound healinges_ES
dc.subjectregenerative medicinees_ES
dc.subjecttissue engineeringes_ES
dc.titleProgress in the Use of Hydrogels for Antioxidant Delivery in Skin Woundses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.date.updated2024-04-27T14:02:51Z
dc.rights.holder© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/ 4.0/).es_ES
dc.relation.publisherversionhttps://www.mdpi.com/1999-4923/16/4/524es_ES
dc.identifier.doi10.3390/pharmaceutics16040524
dc.departamentoesFarmacia y ciencias de los alimentos
dc.departamentoeuFarmazia eta elikagaien zientziak


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© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/ 4.0/).
Except where otherwise noted, this item's license is described as © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/ 4.0/).