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An SPM-Enriched Marine Oil Supplement Shifted Microglia Polarization toward M2, Ameliorating Retinal Degeneration in rd10 Mice
(MDPI, 2022-12-30)
Retinitis pigmentosa (RP) is the most common inherited retinal dystrophy causing progressive vision loss. It is accompanied by chronic and sustained inflammation, including M1 microglia activation. This study evaluated the ...
Modificación del proceso de oxidación de aceites comestibles poliinsaturados por efecto de su enriquecimiento en algunos compuestos con potencial capacidad antioxidante y por efecto de la temperatura.
(2023-02-17)
En la presente memoria para optar al grado de doctor se presenta un resumen de los resultados y las conclusiones más importantes extraídas de los estudios llevados a cabo con el fin de elucidar el efecto que tiene, por un ...
Chitosan-based nanoscale systems for doxorubicin delivery: Exploring biomedical application in cancer therapy
(Wiley, 2023-01)
Green chemistry has been a growing multidisciplinary field in recent years showing great promise in biomedical applications, especially for cancer therapy. Chitosan (CS) is an abundant biopolymer derived from chitin and ...
Caracterización clínico-genética de pacientes con iPPSD y aproximación a la transfección de células madre mesenquimales derivadas de orina mediante niosomas catiónicos
(2022-03-02)
El término iPPSD (inactivating PTH/PTHrP signalling disorder) hace referencia a un grupo de enfermedades (epi)genéticas raras caracterizadas todas ellas por una disfunción en la cascada de señalización de PTH/PTHrP. En la ...
Three-dimensional printing as a cutting-edge, versatile and personalizable vascular stent manufacturing procedure:Toward tailor-made medical devices
(WHIOCE, 2023)
Vascular stents (VS) have revolutionized the treatment of cardiovascular diseases, as evidenced by the fact that the implantation of VS in coronary artery disease (CAD) patients has become a routine, easily approachable ...
Relationship between changes in microbiota induced by resveratrol and its anti-diabetic effect on type 2 diabetes
(Frontiers Media, 2023-01)
Although a general healthy gut microbiota cannot be defined due to numerous internal and external individual factors, such as sex, age, ethnicity, genetics, environment, diet and drugs affect its composition, certain ...
Cri-du-chat syndrome mimics Silver-Russell syndrome depending on the size of the deletion: a case report
(Biomed Central, 2018-12-27)
BackgroundSilver-Russell Syndrome (SRS) is a rare growth-related genetic disorder mainly characterized by prenatal and postnatal growth failure. Although molecular causes are not clear in all cases, the most common mechanisms ...
Effects of Leucine-Enriched Whey Protein Supplementation on Physical Function in Post-Hospitalized Older Adults Participating in 12-Weeks of Resistance Training Program: A Randomized Controlled Trial
(MDPI, 2019-10-01)
Age-related strength and muscle mass loss is further increased after acute periods of inactivity. To avoid this, resistance training has been proposed as an effective countermeasure, but the additional effect of a protein ...
Nanomedicine for autophagy modulation in cancer therapy: a clinical perspective
(BMC, 2023-03)
In recent years, progress in nanotechnology provided new tools to treat cancer more effectively. Advances in biomaterials tailored for drug delivery have the potential to overcome the limited selectivity and side effects ...
Beneficial Effects of Viable and Heat-Inactivated Lactobacillus rhamnosus GG Administration on Oxidative Stress and Inflammation in Diet-Induced NAFLD in Rats
(MDPI, 2023-03-14)
Oxidative stress and inflammation are well-known triggers of NAFLD onset and progression. The aim of this study is to compare the potential benefits of a viable probiotic (Lactobacillus rhamnosus GG) and its parabiotic ...