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Assessment of Hydroxychloroquine Retinal Toxicity in Systemic Lupus Erythematosus in Arab Emirati Patients.
(2023-02-02)
Hydroxychloroquine (HCQ) has a central role for long-term treatment in all lupus patients. Given the broad spectrum of beneficial effects, HCQ is given to most patients with lupus during the whole course of the disease, ...
Traumatic Brain Injury-induced alterations in Adult Hippocampal Neurogenesis
(2023-01-20)
Several important cognitive functions affected by traumatic brain injury (TBI) depend on the hippocampus, which harnesses several forms of neural plasticity, among them adult neurogenesis, the generation of new neurons ...
Analysis of different strategies for in vitro diagnosis of human humoral biomarkers based on solid support immobilization
(2023-11-03)
The study of biomarkers and their detection in human fluids represents one of the best ways to improve the diagnosis and prevention of diseases. The use of human fluids for biomarker analysis can facilitate a friendly and ...
The allosteric control mechanisms of alpha-glucan biosynthesis in bacteria
(2023-10-03)
{EN]The alpha-glucans, polysaccharides made of repetitive units of glucose, play a role as energy storage, as with intracellular glycogen, or as structural components, as with the capsular alpha-glucans surrounding the ...
Synaptic alterations in the hippocampus of an animal model of progressive parkinsonism and the effect of dopaminergic treatments
(2022-03-04)
This Ph.D. project is focused on the characterization of pathological events in the hippocampus, which could be related to non-motor manifestation in Parkinson's disease such as behavioral and memory impairments. For that ...
Application of a battery of cell and tissue level biomarkers in mussels (Mytilus sp.) from Arctic and Subarctic latitudes: identification of confounding factors, biomarker baseline values and responsiveness for an integrated environmental health status assessment
(2022-01-21)
El efecto de los factores ecológicos y fisiológicos influyen de manera drástica en las respuestas biológicas medidas en organismos centinela como los mejillones (Mytilus sp.) haciendo que la evaluación de la salud ...
Adaptación al euskera del Cuestionario Educativo Clínico: Ansiedad y Depresión. Relación de la ansiedad y la depresión con la autoestima, la empatía, el acoso escolar y el apego.
(2023-05-02)
Dado el impacto personal, social y económico de los trastornos de ansiedad y depresión, en esta tesis se plantearon 3 objetivos principales. El primer objetivo principal consistió en adaptar al euskera el Cuestionario ...
Interaction of the LC3/GABARAP autophagy proteins with membranes: Exploring the effects of ceramide
(2023-07-21)
La macroautofagia es un proceso que ocurre en los organismos eucariotas, se caracteriza por la formación del autofagosoma, una estructura de doble membrana encargada de rodear los componentes celulares que se degradan ...
Exploring the transcriptional hallmarks of aging using single-cell RNA sequencing
(2023-11-14)
Aging is associated with a series of phenotypic changes at the cellular level, including changes in gene expression. In recent years, aged tissues have been reported to present an increase in transcriptional noise or ...
MikroRNAen potentziala B Zelula Handiko Linfoma Hedatsuaren diagnostiko, sailkapen eta pronostikoan
(2021-07-28)
Potencial de los microRNAs en el diagnóstico, clasificación y pronóstico del linfoma difuso de células grandes BEl Linfoma difuso de células grandes B (LDCGB) es la neoplasia maligna linfoide más común en adultos y representa ...