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A Computational Analysis of Protein-Protein Interaction Networks in Neurodegenerative Diseases
(Biomed Central, 2008-06-20)
Background: Recent developments have meant that network theory is making an important contribution to the topological study of biological networks, such as protein-protein interaction (PPI) networks. The identification of ...
Three-dimensional growth as multicellular spheroid activates the proangiogenic phenotype of colorectal carcinoma cells via LFA-1-dependent VEGF: implications on hepatic micrometastasis
(BioMed Central, 2008-10)
Background: The recruitment of vascular stromal and endothelial cells is an early event occurring during cancer cell growth at premetastatic niches, but how the microenvironment created by the initial three-dimensional ...
Phosphorylation of the carboxy-terminal domain of histone H1: effects on secondary structure and DNA condensation
(Oxford University Press, 2008-08)
Linker histone H1 plays an important role in chromatin folding. Phosphorylation by cyclin-dependent kinases is the main post-translational modification of histone H1. We studied the effects of phosphorylation on the secondary ...
Long-chain n-3 polyunsaturated fatty acid from fish oil modulates aortic nitric oxide and tocopherol status in the rat
(Cambridge University Press, 2008-10)
In spite of their high oxidisability. long-chain n-3 PUFA protect against CVD. Dietary fatty acids modulate the fatty acid composition of lipoproteins involved in atherosclerosis. We thought that if long-chain n-3 PUFA ...
Tumor necrosis factor alpha drugs in rheumatoid arthritis: systematic review and metaanalysis of efficacy and safety
(BioMed Central, 2008-04-17)
Background: To analyse available evidence on the efficacy and safety of anti-TNF alpha drugs (infliximab, etanercept and adalimumab) for treating rheumatoid arthritis (RA).
Methods: We searched systematically for randomised ...
About the properties of a modified generalized Beverton-Holt equation in ecology models
(Hindawi Publishing Corporation, 2008)
This paper is devoted to the study of a generalized modified version of the well-known Beverton-Holt equation in ecology. The proposed model describes the population evolution of some species in a certain habitat driven ...
On minimal realizations and minimal partial realizations of linear time-invariant systems subject to point incommensurate delays
(Hindawi Publishing Corporation, 2008)
This paper investigates key aspects of realization and partial realization theories for linear time-invariant systems being subject to a set of incommensurate internal and external point delays. The results are obtained ...
Subcutaneous fat composition of youthful and mature Canadian beef: emphasis on individual conjugated linoleic acid and trans-18:1 isomers
(Agricultural Institute of Canada, 2008-12)
[EN]A comprehensive evaluation of the fatty acid composition of subcutaneous adipose tissue from beef cattle produced in western Canada was undertaken to determine if the current Canadian grading system is able to distinguish ...
Model-matching-based control of the Beverton-Holt equation in Ecology
(Hindawi Publishing Corporation, 2008)
Beverton-Holt equation of Ecology has a prescribed solution. The way used to achieve the tracking objective is the design of a carrying capacity through a feedback law so that the prescribed reference sequence, which defines ...
Stability Results for Switched Linear Systems with Constant Discrete Delays
(Hindawi Publishing Corporation, 2008)
This paper investigates the stability properties of switched systems possessing several parameterizations (or configurations) while being subject to internal constant point delays. Some of the stability results are formulated ...