BackExaminar Artículos por departamento (eus.) "Medikuntza"
Now showing items 61-80 of 175
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Exome Sequencing of Early-Onset Patients Supports Genetic Heterogeneity in Colorectal Cancer
Fernández Rozadilla, Ceres; Álvarez Barona, M.; Quintana, I.; López Novo, A.; Amigo, J.; Cameselle Teijeiro, J. M.; Román, E.; González, Dolors; Llor, Xavier; Bujanda Fernández de Pierola, Luis
; Bessa, Xavier; Jover, Rodrigo; Balaguer, Francesc; Castells, Antoni; Castellví Bel, Sergi; Capella, Gabriel; Carracedo, Angel; Valle, Laura; Ruiz Ponte, Clara (Springer, 2021-05-27)
Colorectal cancer (CRC) is a complex disease that can be caused by a spectrum of genetic variants ranging from low to high penetrance changes, that interact with the environment to determine which individuals will develop ... -
Experience with Rifabutin-Containing Therapy in 500 Patients from the European Registry on Helicobacter pylori Management (Hp-EuReg)
; ; ; ; ; Bujanda Fernández de Pierola, Luis; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; (MDPI, 2022-03-16)
Background: First-line Helicobacter pylori (H. pylori) treatments have been relatively well evaluated; however, it remains necessary to identify the most effective rescue treatments. Our aim was to assess the effectiveness ... -
Expression and activity of angiotensin-regulating enzymes is associated with prognostic outcome in clear cell renal cell carcinoma patients
Errarte Yarza, Peio; Beitia San Vicente, Maider; Pérez Urzelai, Itxaro; Manterola, Lorea; Lawrie, Charles; Solano Iturri, Jon Danel; Calvete Candenas, Julio; Unda Urzaiz, Jesús Miguel; López, José I.; Larrinaga Embeita, Gorka (Public Library Science, 2017-08-15)
The discovery of the intrarenal renin-angiotensin system (iRAS), which regulates angiogenesis, cell differentiation and proliferation, has opened new perspectives in the knowledge of kidney carcinogenesis. In this study ... -
Extracellular Vesicles in Hepatobiliary Malignancies
; ; ; ; Bujanda Fernández de Pierola, Luis; ; Bañales Asurmendi, Jesús María (Frontiers Media, 2018-10-12)
Primary hepatobiliary malignancies include a heterogeneous group of cancers with dismal prognosis, among which hepatocellular carcinoma (HCC), cholangiocarcinoma (CCA), and hepatoblastoma (HB) stand out. These tumors mainly ... -
Extracellular Vesicles in Liver Diseases: Meeting Report from the International Liver Congress 2018
Bañales Asurmendi, Jesús María; Feldstein, Ariel E.; Sänger, Hanna; Lukacs-Kornek, Veronika; Szabo, Gyongyi; Kornek, Miroslaw (Wiley, 2019-02)
Extracellular vesicles (EVs) are small and heterogeneous membrane-bound structures released by cells and found in all biological fluids. They are effective intercellular communicators, acting on a number of close and/or ... -
Factores de riesgo y supervivencia libre de tumor en pacientes con trasplante renal de cadáver
; Virto Moreno, Jorge; Orbe Lizundia, Jesús María ; ; ; Gainza Ríos, Francisco Javier ; ; (2003)
[Background] There is an agreement in the fact that cancer incidence in transplant recipients increases at a rate disproportionately greater than in the general population. Several clinical studies have identified cancer ... -
Factors associated with successful dietary changes in an energy-reduced Mediterranean diet intervention: a longitudinal analysis in the PREDIMED-Plus trial
; Alonso Gómez, Ángel María (Springer, 2022)
[EN] Purpose Long-term nutrition trials may fail to respond to their original hypotheses if participants do not comply with the intended dietary intervention. We aimed to identify baseline factors associated with successful ... -
Fatty Acid Profile of Mature Red Blood Cell Membranes and Dietary Intake as a New Approach to Characterize Children with Overweight and Obesity
Jauregibeitia, Iker; Portune, Kevin; Rica, Itxaso; Tueros, Itziar; Velasco, Olaia; Grau, Gema; Trebolazabala, Nerea; Castaño González, Luis Antonio; Larocca, Anna Vita; Ferreri, Carla; Arranz, Sara (MDPI, 2020-11-10)
Obesity is a chronic metabolic disease of high complexity and of multifactorial origin. Understanding the effects of nutrition on childhood obesity metabolism remains a challenge. The aim of this study was to determine the ... -
Fibromialgia: adversidad desde el sistema sanitario
Muñoa Capron Manieux, María; Gandarias Olaran, Leticia (Elsevier, 2022-03)
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Fine-Tuning of Sirtuin 1 Expression Is Essential to Protect the Liver From Cholestatic Liver Disease
Blokker, Britt A.; Maijo, Monica; Echeandia, Marta; Galduroz, Mikel; Patterson, Angela M.; Ten, Anna; Philo, Mark; Schungel, Rebecca; Gutierrez de Juan, Virginia; Halilbasic, Emina; Fuchs, Claudia; Le Gall, Gwenaelle; Milkiewicz, Malgorzata; Milkiewicz, Piotr; Bañales Asurmendi, Jesús María; Rushbrook, Simon M.; Mato, José M.; Trauner, Michael; Müller, Michael; Martínez-Chantar, María Luz; Varela Rey, Marta; Beraza, Naiara (Wiley, 2019-02)
Cholestasis comprises aetiologically heterogeneous conditions characterized by accumulation of bile acids in the liver that actively contribute to liver damage. Sirtuin 1 (SIRT1) regulates liver regeneration and bile acid ... -
Five Patients with Disorders of Calcium Metabolism Presented with GCM2 Gene Variants
García Castaño, Alejandro; Madariaga Domínguez, Leire; Gómez Conde, Sara; Rey Cordo, Carmen Lourdes; López Iglesias, María; García Fernández, Yolanda; Martín Nieto, Alicia; González, Pedro; Goicolea, Ignacio; Pérez de Nanclares, Gustavo; De la Hoz, Ana Belén; Aguayo Calcena, Aníbal; Martínez de la Piscina Martín, Idoia; Martínez Salazar, Rosa; Saso Jiménez, Laura; Urrutia, Inés; Velasco, Olaia; Castaño González, Luis Antonio ; Gaztambide Sáenz, María Sonia (Nature, 2021-02-03)
The GCM2 gene encodes a transcription factor predominantly expressed in parathyroid cells that is known to be critical for development, proliferation and maintenance of the parathyroid cells. A cohort of 127 Spanish patients ... -
Fluctuation and change of serum urate levels and flares in gout: results from the NOR-Gout study
(Springer, 2022)A gout attack may evolve after a purine-rich diet or alcohol and after starting urate-lowering therapy (ULT). The relationships between fluctuation and change in serum urate (SU) with the occurrence of flares were investigated ... -
FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; Ávila, Matías A.; ; ; ; ; Bañales Asurmendi, Jesús María ; (Elsevier, 2021-04-20)
[EN] Background & Aims: Cholangiocarcinoma (CCA) is a neoplasia of the biliary tract driven by genetic, epigenetic and transcriptional mechanisms. Herein, we investigated the role of the transcription factor FOSL1, as ... -
Fruit and Vegetable Consumption is Inversely Associated with Plasma Saturated Fatty Acids at Baseline in Predimed Plus Trial
; ; ; ; ; ; ; ; ; ; Alonso Gómez, Ángel María; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; (Wiley, 2021-09)
Scope Plasma fatty acids (FAs) are associated with the development of cardiovascular diseases and metabolic syndrome. The aim of our study is to assess the relationship between fruit and vegetable (F&V) consumption and ... -
Functional rare variants influence the clinical response to anti-TNF therapy in Crohn's disease
PREDICROHN Study Group GETECCU; Bujanda Fernández de Pierola, Luis; Bañales Asurmendi, Jesús María (Sage, 2019-09)
Background: The effect of low-frequency functional variation on anti-tumor necrosis factor alpha (TNF) response in Crohn's disease (CD) patients remains unexplored. The objective of this study was to investigate the impact ... -
Functional recovery in patients with schizophrenia: recommendations from a panel of experts
Lahera, Guillermo; Gálvez, José L.; Sánchez Gómez, Pedro María; Martínez-Roig, Miguel; Pérez-Fuster, J. V.; García-Portilla, Paz; Herrera, Berta; Roca, Miquel (Biomed Central, 2018-06-05)
emission and encompasses multiple aspects of the patient's life, making it difficult to settle on a definition and to develop reliable assessment criteria. In this consensus process based on a panel of experts in schizophrenia, ... -
Genetic Variants as Predictors of the Success of Colorectal Cancer Treatments
; ; ; ; ; ; ; ; ; Bujanda Fernández de Pierola, Luis (MDPI, 2023-09-22)
Some colorectal cancer (CRC) outcomes are partially associated with genetics, and different studies have proposed several genetic variants as predictors. However, analysis of their performance in other populations is ... -
Genetic Variants Associated with Colorectal Adenoma Susceptibility
Abulí, Anna; Castells, Antoni; Bujanda Fernández de Pierola, Luis; Lozano, Juan José; Bessa, Xavier; Hernández, Cristina; Álvarez-Urturi, Cristina; Pellisé, María; Esteban-Jurado, Clara; Hijona Muruamendiaraz, Elizabeth; Burón, Andrea; Macià, Francesc; Grau, Jaume; Guayta, Rafael; Castellví-Bel, Sergi; Andreu, Montserrat; PROCOLON research group (PUBLIC LIBRARY SCIENCE, 2016-04-14)
Background Common low-penetrance genetic variants have been consistently associated with colorectal cancer risk. Aim To determine if these genetic variants are associated also with adenoma susceptibility and may ... -
Gut microbiome and serum metabolome analyses identify molecular biomarkers and altered glutamate metabolism in fibromyalgia
; ; ; Abecia Aliende, Leticia; ; ; ; ; ; ; ; ; ; ; ; ; Bujanda Fernández de Pierola, Luis ; ; ; ; ; (Elsevier, 2019-08)
Background: Fibromyalgia is a complex, relatively unknown disease characterised by chronic, widespread musculoskeletal pain. The gut-brain axis connects the gut microbiome with the brain through the enteric nervous system ... -
Health information use by patients with systemic lupus erythematosus (SLE) pre and during the COVID-19 pandemic
(BMJ, 2022)Objective We conducted an international survey of patients with SLE to assess their access, preference and trust in various health information sources pre-COVID-19 and during the COVID-19 pandemic. Methods Patients with ...