BackExaminar Artículos por departamento (eus.) "Medikuntza"
Now showing items 41-60 of 175
-
Development and external validation of a faecal immunochemical test-based prediction model for colorectal cancer detection in symptomatic patients
Cubiella, Joaquín; Vega, Pablo; Salve, María; Díaz-Ondina, Marta; Alves, Maria Teresa; Quintero, Enrique; Álvarez-Sánchez, Victoria; Fernández-Bañares, Fernando; Boadas, Jaume; Campo, Rafel; Bujanda Fernández de Pierola, Luis
; Clofent, Joan; Ferrandez, Ángel; Torrealba, Leyanira; Piñol, Virginia; Rodríguez-Alcalde, Daniel; Hernández, Vicent; Fernández-Seara, Javier; COLONPREDICT study investigators (Biomed Central, 2016-08-31)
Background: Risk prediction models for colorectal cancer (CRC) detection in symptomatic patients based on available biomarkers may improve CRC diagnosis. Our aim was to develop, compare with the NICE referral criteria and ... -
Diastolic Dysfunction and Exercise Capacity in Patients with Metabolic Syndrome and Overweight/Obesity
Alonso Gómez, Ángel María; Tojal Sierra, Lucas; Fortuny Frau, Elena; Goicolea Güemez, Leire; Aboitiz Uribarri, Ane; Portillo Baquedano, María Puy ; Toledo, Estefanía; Schröder, Helmut; Salas Salvadó, Jordi; Arós Borau, Luis Fernando (Elsevier, 2019-03)
Background: Left ventricle diastolic dysfunction (LVDD) is a common finding in high risk individuals, its presence being associated with reduced exercise capacity (EC). We assessed the prevalence of LVDD, applying the 2016 ... -
Dietary diversity and depression: cross-sectional and longitudinal analyses in Spanish adult population with metabolic syndrome. Findings from PREDIMED-Plus trial
; ; ; ; ; ; ; ; Alonso Gómez, Ángel María; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; (Cambridge University Press, 2023-03)
Objective: To examine the cross-sectional and longitudinal (2-year follow-up) associations between dietary diversity (DD) and depressive symptoms. Design: An energy-adjusted dietary diversity score (DDS) was assessed ... -
Dietary Diversity and Nutritional Adequacy among an Older Spanish Population with Metabolic Syndrome in the PREDIMED-Pl us Study:A Cross-Sectional Analysis
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; Alonso Gómez, Ángel María; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; (MDPI, 2019-04-26)
Dietary guidelines emphasize the importance of a varied diet to provide an adequate nutrient intake. However, an older age is often associated with consumption of monotonous diets that can be nutritionally inadequate, ... -
Dietary Intake in Population with Metabolic Syndrome: Is the Prevalence of Inadequate Intake Influenced by Geographical Area? Cross-Sectional Analysis from PREDIMED-Plus Study
; ; ; ; ; ; ; ; ; ; ; ; ; Alonso Gómez, Ángel María; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; (MDPI, 2018-11-04)
Inadequate diet influences chronic diseases such as cardiovascular disease (CVD), the leading cause of death in Spain. CVD figures vary from one geographical region to another; this could be associated with different food ... -
Differential activity of GSK-3 isoforms regulates NF-kappa B and TRAIL- or TNF alpha induced apoptosis in pancreatic cancer cells
Zhang, J.S.; Herreros Villanueva, Marta; Koenig, A.; Deng, Z.; M De Narvajas, A. A.; Gómez, T. S.; Meng, X.; Bujanda Fernández de Pierola, Luis; Ellenrieder, V.; Li, X. K.; Kaufmann, S. H.; Billadeau, D. D. (Nature Publishing Group, 2014-03)
While TRAIL is a promising anticancer agent due to its ability to selectively induce apoptosis in neoplastic cells, many tumors, including pancreatic ductal adenocarcinoma (PDA), display intrinsic resistance, highlighting ... -
Differentially Deregulated MicroRNAs as Novel Biomarkers for Neoplastic Progression in Ulcerative Colitis.
; ; ; ; ; ; ; Bujanda Fernández de Pierola, Luis; ; ; ; ; ; ; ; ; ; (Wolters Kluwer, 2022)
INTRODUCTION: Colorectal cancer (CRC) is a potentially life-threatening complication of long-standing ulcerative colitis (UC). MicroRNAs (miRNA) are epigenetic regulators that have been involved in the development of ... -
Discoidin Domain Receptor 2 Expression as Worse Prognostic Marker in Invasive Breast Cancer
Romayor Arredondo, Irene; Luque García Vaquero, Marina; Márquez Clavijo, Joana ; Arteta Ruiz, Beatriz ; Barceló Galíndez, José Ramón; Benedicto García, Aitor (Wiley, 2022)
[EN] Discoidin domain receptor 2 (DDR2) is arising as a promising therapeutic target in breast carcinoma (BC). The ability of DDR2 to bind to collagen promotes protumoral responses in cancer cells that influence the tumor ... -
Documento de consenso para el manejo de la esquistosomiasis en atención primaria
(Elsevier, 2022-08)Human schistosomiasis is the parasitic disease with the highest morbidity and morta-lity worldwide after malaria. It is endemic in more than 78 tropical and subtropical countries, especially in sub-Saharan Africa, and it ... -
Dysautonomia in COVID-19 Patients: A Narrative Review on Clinical Course, Diagnostic and Therapeutic Strategies
(Frontiers Media, 2022-05)IntroductionOn March 11, 2020, the World Health Organization sounded the COVID-19 pandemic alarm. While efforts in the first few months focused on reducing the mortality of infected patients, there is increasing data on ... -
Effect of an Intensive Lifestyle Intervention on Circulating Biomarkers of Atrial Fibrillation-Related Pathways among Adults with Metabolic Syndrome: Results from a Randomized Trial
; ; ; Alonso Gómez, Ángel María; ; ; ; ; ; ; ; (MDPI, 2024-04-07)
Background: Lifestyles influence atrial fibrillation (AF) risk. Determining the effect of lifestyle interventions on blood concentrations of biomarkers of AF-related pathways could help understand AF pathophysiology and ... -
Effectiveness of a Structured Group Intervention Based on Pain Neuroscience Education for Patients with Fibromyalgia in Primary Care: a Multicentre Randomized Open-Label Controlled Trial
; Muñoa Capron Manieux, María; ; ; ; ; ; ; ; ; Zorrilla Artero, Ana Isabel ; Larrinaga Embeita, Gorka ; ; (Wiley, 2021-05)
Background There has been increased interest in pain neuroscience education (PNE) as a therapeutic approach for the management of fibromyalgia (FM). Methods A multicentre randomized, open-label, controlled trial was ... -
Effectiveness of the physical activity intervention program in the PREDIMED-Plus study: a randomized controlled trial
(Biomed Central, 2018-11-13)BackgroundThe development and implementation of effective physical activity (PA) intervention programs is challenging, particularly in older adults. After the first year of the intervention program used in the ongoing ... -
Effects of Leucine-Enriched Whey Protein Supplementation on Physical Function in Post-Hospitalized Older Adults Participating in 12-Weeks of Resistance Training Program: A Randomized Controlled Trial
Amasene Ugalde, María; Besga, Ariadna; Echeverria, Iñaki; Urquiza Abaunza, Miriam ; Ruiz, Jonatan R.; ; Aldamiz-Echebarria San Sebastian, Mikel; Anaut, Pilar; Irazusta Astiazaran, Jon ; Labayen Goñi, Idoya (MDPI, 2019-10-01)
Age-related strength and muscle mass loss is further increased after acute periods of inactivity. To avoid this, resistance training has been proposed as an effective countermeasure, but the additional effect of a protein ... -
Effects of Resistance Training Intervention along with Leucine-Enriched Whey Protein Supplementation on Sarcopenia and Frailty in Post-Hospitalized Older Adults: Preliminary Findings of a Randomized Controlled Trial
Amasene Ugalde, María; Cadenas-Sanchez, Cristina; Echeverria Garay, Iñaki ; Sanz Echevarría, María Begoña; Alonso, Cristina; Tobalina Larrea, Ignacio; Irazusta Astiazaran, Jon ; Labayen Goñi, Idoya ; Besga Basterra, Ariadna (MDPI, 2021-12-24)
Resistance training and protein supplementation are expected to exert the greatest effect in counteracting muscle-wasting conditions. Myokines might play a key role, but this remains to be elucidated. The aim of this study ... -
Eficacia de un Programa Multidisciplinar de Gestión de Cuidados en Pacientes que Ingresan por Insuficiencia Cardiaca (ProMIC)
(Doyma, 2019-03)Objetivo: Evaluar la eficacia de « ProMIC » , programa multidisciplinar de atención a pacientes con insuficiencia cardiaca (IC), para reducir de la tasa de reingresos por IC. Dise ̃ no: En ... -
Erythrocyte Membrane Nanomechanical Rigidity Is Decreased in Obese Patients
Sot, Jesús; García Arribas, Aritz; Abad García, Beatriz; Arranz, Sara; Portune, Kevin; Andrade, Fernando; Martín Nieto, Alicia; Velasco, Olaia; Arana, Eunate; Tueros, Itziar; Ferreri, Carla; Gaztambide Sáenz, María Sonia; Goñi Urcelay, Félix María ; Castaño González, Luis Antonio ; Alonso Izquierdo, Alicia (MDPI, 2022-02-08)
This work intends to describe the physical properties of red blood cell (RBC) membranes in obese adults. The hypothesis driving this research is that obesity, in addition to increasing the amount of body fat, will also ... -
Evaluation of Alpha 1-Antitrypsin and the Levels of mRNA Expression of Matrix Metalloproteinase 7, Urokinase Type Plasminogen Activator Receptor and COX-2 for the Diagnosis of Colorectal Cancer
Bujanda Fernández de Pierola, Luis; ; ; ; Enríquez Navascués, José María ; ; ; ; ; ; ; (Public Library of Science, 2013-01-02)
Background: Colorectal cancer (CRC) is the second most common cause of death from cancer in both men and women in the majority of developed countries. Molecular tests of blood could potentially provide this ideal screening ... -
Evidence for classification of c.1852_1853AA > GC in MLH1 as a neutral variant for Lynch syndrome
Castillejo, Adela; Guarinos, Carla; Martínez Canto, Ana; Barberá, Víctor Manuel; Egoavil, Cecilia; Castillejo, María Isabel; Pérez Carbonell, Lucía; Sánchez Heras, Ana Beatriz; Segura, Angel; Ochoa, Enrique; Lázaro, Rafael; Ruiz Ponte, Clara; Bujanda Fernández de Pierola, Luis; Andreu, Montserrat; Castells, Antoni; Carracedo, Angel; Llor, Xavier; Clofent, Juan; Alenda, Cristina; Paya, Artemio; Jover, Rodrigo; Soto, José Luis (BioMed Central, 2011-01)
Background: Lynch syndrome (LS) is an autosomal dominant inherited cancer syndrome characterized by early onset cancers of the colorectum, endometrium and other tumours. A significant proportion of DNA variants in LS ... -
Evidence of conditioned behavior in amoebae
Martínez de la Fuente Martínez, Ildefonso Abel; Bringas Roldán, Carlos; Malaina Celada, Iker; Fedetz, María; Carrasco Pujante, José; Morales, Miguel; Knafo Farhi, Dina Shira; Martínez Fernández, Luis ; Pérez Samartín, Alberto Luis ; López Fernández de Villaverde, José Ignacio ; Pérez-Yarza Pérez-Irezabal, Gorka ; Boyano López, María Dolores (Nature, 2019-08-15)
Associative memory is the main type of learning by which complex organisms endowed with evolved nervous systems respond efficiently to certain environmental stimuli. It has been found in different multicellular species, ...