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High Biofilm Formation of Non-Smooth Candida parapsilosis Correlates with Increased Incorporation of GPI-Modified Wall Adhesins
(MDPI, 2021-04-19)
Candida parapsilosis is among the most frequent causes of candidiasis. Clinical isolates of this species show large variations in colony morphotype, ranging from round and smooth to a variety of non-smooth irregular colony ...
Candida albicans biofilms on different materials for manufacturing implant abutments and prostheses
(Medicina Oral S. L., 2020-01-01)
[EN] Background: Morphological, physical and chemical properties of both implants and prostheses can determine the
biofilm formation on their surface and increase the risk of biological complications. The aim of this study ...
Antimicrobial Peptides with Anti-Candida Activity
(MDPI, 2022-08-17)
[EN] Mycoses are accountable for millions of infections yearly worldwide. Invasive candidiasis is the most usual, presenting a high morbidity and mortality. Candida albicans remains the prevalent etiologic agent, but the ...
Candida duobushaemulonii: An Old But Unreported Pathogen
(MDPI, 2020-12-17)
Candidiasis caused by species of the Candida haemulonii complex (Candida haemulonii and Candida duobushaemulonii) and closely related species, Candida auris and Candida pseudohaemulonii are increasing. These species often ...
Virulence of Candida Auris from Different Clinical Origins in Caenorhabditis Elegans and Galleria Mellonella Host Models
(Taylor & Francis, 2021-01-01)
Candida auris is an emerging multidrug-resistant fungal pathogen responsible for nosocomial outbreaks of invasive candidiasis. Although several studies on the pathogenicity of this species have been reported, the knowledge ...
In vitro and in vivo anti-Candida activity of citral in combination with fluconazole
(Taylor & Francis, 2022)
[EN] Background The ability of Candida to develop biofilms on inert surfaces or living tissues favors recalcitrant and chronic candidiasis associated, in many instances, with resistance to current antifungal therapy. Aim ...
In Vitro and In Vivo Activity of Citral in Combination with Amphotericin B, Anidulafungin and Fluconazole against Candida auris Isolates
(MDPI, 2023-06-06)
Candida auris is an emerging fungal pathogen responsible for hospital outbreaks of invasive candidiasis associated with high mortality. The treatment of these mycoses is a clinical challenge due to the high resistance ...
Design and validation of a multiplex PCR protocol for microsatellite typing of Candida parapsilosis sensu stricto isolates
(Biomed Central, 2018-09-29)
Background: Analysis of polymorphic microsatellite markers (STR) is a helpful genotyping technique to differentiate Candida parapsilosis sensu stricto isolates. The aim of this study is to develop and perform an initial ...
Assessing pH-dependent activities of virulence factors secreted by Candida albicans
(Wiley, 2023-02)
Candida albicans is an opportunistic pathogen that can thrive under adverse conditions including suboptimal pH, nutrient scarcity, and low levels of oxygen. Its pathogenicity is associated with the production of virulence ...
Postantifungal Effect of Antifungal Drugs against Candida: What Do We Know and How Can We Apply This Knowledge in the Clinical Setting?
(MDPI, 2022)
The study of the pharmacological properties of an antifungal agent integrates the drug pharmacokinetics, the fungal growth inhibition, the fungicidal effect and the postantifungal activity, laying the basis to guide optimal ...