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A statistical investigation into the sharing of common genetic factors between blood pressure and obesity phenotypes in nuclear families from the Greater Bilbao (Spain)
(Lippincott, Williams & Wilkins, 2010)
Objectives: Several obesity phenotypes (e.g. body mass and fat, fat distribution) have been suggested to be a risk for elevated blood pressure. This study was undertaken to determine the heritability of four blood pressure ...
Translating propositional extended conjunctions of Horn clauses into Boolean circuits
(Elsevier, 2010-01-25)
Horn⊃ is a logic programming language that extends usual Horn clauses by adding intuitionistic implication in goals and clause bodies. This extension can be seen as a way of structuring programs in logic programming. We ...
DNA methylation epigenotypes in breast cancer molecular subtypes
(BioMed Central, 2010-09-29)
Introduction: Identification of gene expression-based breast cancer subtypes is considered a critical means of prognostication. Genetic mutations along with epigenetic alterations contribute to gene-expression changes ...
Structure and Stability of the Endohedrally Doped (X@CdS) X=Na,K,Cl,Br Nanoclusters.
(ACS, 2010-01-27)
Endohedral (X@CdiSi)q=0,±1 structures have been characterized by means of the density functional theory with X being alkali metals such as Na and K or halogens such as Cl and Br and with i = 4, 9, 12, 15, 16. These ...
Analysis of the turning circle manoeuvre from the point of view of an efficient managing of the main engine
(Spanish Society of Maritime Research (SEECMAR), 2010-08)
The purpose of this paper is to study the influence of the 360 deg turn in theeconomy of the voyage and to find out the maximum efficiency by means of themain engine’s procedure. Moreover ...
Detecting depression in medically ill patients: comparative accuracy of four screening questionnaires and physicians' diagnoses in Spanish population
(2010-10)
Objective: To compare the diagnostic accuracy of four depression screening tools commonly used in patients with medical disorders, relative to a reference diagnostic standard – a structured psychiatric interview.
Methods: ...
Characterization of a mouse model overexpressing beta-site APP-cleaving enzyme 2 reveals a new role for BACE2
(Wiley, 2010-03-10)
BACE2 is homologous to BACE1, a beta-secretase that is involved in the amyloidogenic pathway of amyloid precursor protein (APP), and maps to the Down syndrome critical region of chromosome 21. Alzheimer disease neuropathology ...
Classification of archaeological pieces into their respective stratum by a chemometric model based on the soil concentration of 25 selected elements
(Elsevier, 2010-04-01)
The aim of this work was to demonstrate that an archaeological ceramic piece has remained buried underground in the same stratum for centuries without being removed. For this purpose, a chemometric model based on Principal ...
Engineering DYRK1A over-dosage yields Down syndrome-characteristic cortical splicing aberrations
(Elsevier, 2010-10)
Down syndrome (DS) associates with impaired brain functions, but the underlying mechanism(s) are yet unclear. The "gene dosage" hypothesis predicts that in DS, overexpression of a single gene can impair multiple brain ...
Goizueta Basque
(2010-03-15)
Goizueta is a small town in northwestern Navarre, Spain, bordering Gipuzkoa. According to the most recent official figures, it has slightly over 800 inhabitants, about 95% of whom speak Basque (2001, Instituto de Estadística ...