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In vivo effects of APP are not exacerbated by BACE2 co-overexpression: behavioural characterization of a double transgenic mouse model
(Springer, 2010-07-02)
Down syndrome, the most common genetic disorder leading to mental retardation, is caused by the presence of all or part of an extra copy of chromosome 21. At relatively early ages, Down syndrome patients develop progressive ...
Inhibition of secretion of interleukin (IL)-12/IL-23 family cytokines by 4-trifluoromethyl-celecoxib is coupled to degradation via the endoplasmic reticulum stress protein HERP
(American Society for Biochemistry and Molecular Biology, Inc, 2010-03-05)
Interleukin-12 (IL-12), p80, and IL-23 are structurally related cytokines sharing a p40 subunit. We have recently demonstrated that celecoxib and its COX-2-independent analogue 4-trifluoromethyl-celecoxib (TFM-C) inhibit ...
Unibertsitate-ikasketetako sexu-segregaziora hurbilketa
(Udako Euskal Unibertsitatea, 2010-04)
Gure gizartean sexuen arteko parekotasun instituzionala lortu da hein handi batean, hala ere, hainbat esparrutan berdintasun hori ez da gauzatu. Beste askoren artean, hezkuntza instituzionalaren arloa aipa daiteke, eta ...
Los orígenes de la feminización del magisterio en España: las maestras de la Sociedad Económica de Valencia (1819-1866)
(Universidad de Granada, 2010)
Este artículo pretende abordar la cuestión de los orígenes de la feminización del magisterio en España a través del estudio de las maestras que enseñaron en las escuelas financiadas por la Sociedad Económica de Valencia ...
Prevalence and clonal characterization of Streptococcus pyogenes clinical isolates with reduced fluoroquinolone susceptibility in Spain
(2010-01-01)
The aim of this study was to determine the prevalence and characteristics of non-fluoroquinolone (FQ)-
susceptible Streptococcus pyogenes isolates and to study their mechanisms of resistance. We performed a prospective ...
Speed deficiency in shipbuilding contracts from the point of view of an efficient managing of the main engine
(University of Santander, 2010)
This article is related to the shipbuilding contracts and its purpose is to provide amethod of calculation of the economical damages sustained by a purchaser due tothe speed deficiency of the vessel delivered by the shipyard. ...
El presente y futuro de un bien común: el paisaje de una Reserva de la Biosfera
(Asociación de Geógrafos Españoles, 2010)
En este artículo se presentan como experiencia metodológica el tratamiento y resultados
de un trabajo de diagnóstico y pronóstico paisajístico concretado en la Reserva de la Biosfera
de Urdaibai (País Vasco). Se ha ...
Shell midden people in northern Iberia. New data from the mesolithic rock shelter of J3 (Basque Country, Spain)
(Ediciones Universidad de Salamanca, 2010)
[EN]In the course of a sondage dug in the rock shelter of J3, in the Jaizkibel mountains (at the north-western tip of Guipúzcoa), the body of a adult man was located buried inside a shell midden. This shell midden had not ...