Search
Now showing items 221-230 of 339
Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models of tauopathies
(Taylor & Francis, 2023-02)
Synapses represent an important target of Alzheimer disease (AD), and alterations of their excitability are among the earliest changes associated with AD development. Synaptic activation has been shown to be protective in ...
Endocannabinoid signaling in brain diseases: Emerging relevance of glial cells
(Wiley, 2023-01)
The discovery of cannabinoid receptors as the primary molecular targets of psychotropic cannabinoid Delta(9)-tetrahydrocannabinol (Delta(9)-THC) in late 1980s paved the way for investigations on the effects of cannabis-based ...
Costs and effects of telerehabilitation in neurological and cardiological diseases: A systematic review
(Frontiers Media, 2022)
Introduction: Telerehabilitation in neurological and cardiological diseases is an alternative rehabilitation that improves the quality of life and health conditions of patients and enhances the accessibility to health care. ...
Brain fog of post-COVID-19 condition and Chronic Fatigue Syndrome, same medical disorder?
(BMC, 2022-12)
Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is characterized by persistent physical and mental fatigue. The post-COVID-19 condition patients refer physical fatigue and cognitive impairment ...
Local diffusion in the extracellular space of the brain
(Elsevier, 2023-02)
The brain extracellular space (ECS) is a vast interstitial reticulum of extreme morphological complexity, composed of narrow gaps separated by local expansions, enabling interconnected highways between neural cells. ...
Neurocognition and functioning in adolescents at clinical high risk for psychosis
(BMC, 2023-02)
BACKGROUND: Once psychosis has set in, it is difficult for patients to achieve full recovery. Prevention of psychosis and early intervention are promising for improving the outcomes of this disorder. In the last two decades, ...
Impact of adverse childhood experiences on educational achievements in young people at clinical high risk of developing psychosis
(Oxford University Press, 2023-01)
BACKGROUND: Adverse childhood experiences (ACE) can affect educational attainments, but little is known about their impact on educational achievements in people at clinical high risk of psychosis (CHR).
METHODS: In ...
Risk of suicide attempt repetition after an index attempt: A systematic review and meta-analysis
(Elsevier, 2023-03)
Objectives
To estimate the risk of suicide attempt repetition among individuals with an index attempt. It also aims to study the role of risk factors and prevention programme in repetition.
Methods
This systematic review ...
Regret and therapeutic decisions in multiple sclerosis care: literature review and research protocol
(Frontiers Media, 2021-06-21)
[EN] Background: Decisions based on erroneous assessments may result in unrealistic
patient and family expectations, suboptimal advice, incorrect treatment, or costlymedical
errors. Regret is a common emotion in daily ...
Assessing care-related regret among nurses specialized in multiple sclerosis: A psychometric analysis of a new assessment battery
(SAGE, 2022-10)
Experiences of regret associated with caring for patients with multiple sclerosis (MS) can affect medical decisions. A non-interventional study was conducted to assess the dimensionality and item characteristics of a battery ...