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Lifestyle-dependent microglial plasticity: training the brain guardians
(BMC, 2021-08-03)
Lifestyle is one of the most powerful instruments shaping mankind; the lifestyle includes many aspects of interactions with the environment, from nourishment and education to physical activity and quality of sleep. All ...
Alterations of the Hippocampal Neurogenic Niche in a Mouse Model of Dravet Syndrome
(Frontiers Media, 2020-07-21)
Hippocampal neurogenesis, the process by which neural stem cells (NSCs) continuously generate new neurons in the dentate gyrus (DG) of most mammals including humans, is chiefly regulated by neuronal activity. Thus, severe ...
BASP1 labels neural stem cells in the neurogenic niches of mammalian brain
(Springer Nature, 2021-03-10)
The mechanisms responsible for determining neural stem cell fate are numerous and complex. To begin to identify the specific components involved in these processes, we generated several mouse neural stem cell (NSC) antibodies ...
Quantifying Knowledge of Alzheimer's Disease: an Analysis of the Psychometric Properties of the Alzheimer's Disease Knowledge Scale
(Springer, 2021-06)
Introduction: The Alzheimer's Disease Knowledge Scale (ADKS) is one of the most popular instruments for assessing a person's knowledge regarding Alzheimer's disease (AD). The objective of this study was to explore ADKS ...
Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits
(Elsevier, 2021-01-01)
BACKGROUND: Suicide is a major health concern worldwide, thus, identifying risk factors would enable a more comprehensive understanding and prevention of this behaviour. Neuropsychological alterations could lead to ...
Cognition in Recent Suicide Attempts: Altered Executive Function
(Frontiers Media, 2021-07-22)
Background: Neuropsychological alterations can lead to inaccurate perception, interpretation, and response to environmental information, which could be a risk factor for suicide.
Methods: Ninety-six subjects were recruited ...
Overview of lithium's use: a nationwide survey
(Springer, 2021-03-09)
BACKGROUND: Lithium is considered the gold standard treatment for bipolar disorder (BD). Current clinical guidelines and scientific evidence support its use as a first-line treatment in BD. However, over the last two ...
A qualitative research of adolescents with behavioral problems about their experience in a dialectical behavior therapy skills training group
(BMC, 2020-05-19)
BACKGROUND: Several quantitative studies support the effectiveness of the Dialectical Behavior Therapy (DBT) psychosocial skills training group component for adolescents with impulse-control disorder and/or emotional ...
Proportion and predictors of remission and recovery in first-episode psychosis: Systematic review and meta-analysis
(Cambridge University Press, 2021-11)
[EN] Background To determine the proportion of patients in symptomatic remission and recovery following a first-episode of psychosis (FEP). Methods A multistep literature search using the Web of Science database, Cochrane ...
Gut microbiota, innate immune pathways, and inflammatory control mechanisms in patients with major depressive disorder
(Springer Nature, 2021-12-21)
[EN] Although alterations in the gut microbiota have been linked to the pathophysiology of major depressive disorder (MDD), including through effects on the immune response, our understanding is deficient about the straight ...