dc.contributor.author | Sánchez Villegas, Almudena | |
dc.contributor.author | Álvarez Pérez, Jacqueline | |
dc.contributor.author | Toledo, Estefanía | |
dc.contributor.author | Salas Salvadó, Jordi | |
dc.contributor.author | Ortega Azorín, Carolina | |
dc.contributor.author | Zomeño Fajardo, María Dolores | |
dc.contributor.author | Vioque, Jesús | |
dc.contributor.author | Martínez, José Alfredo | |
dc.contributor.author | Romaguera, Dora | |
dc.contributor.author | Pérez López, Jessica | |
dc.contributor.author | López Miranda, José | |
dc.contributor.author | Estruch, Ramón | |
dc.contributor.author | Bueno Cavanillas, Aurora | |
dc.contributor.author | Arós Borau, Luis Fernando | |
dc.contributor.author | Tur, Josep A. | |
dc.contributor.author | Tinahones, Francisco J. | |
dc.contributor.author | Lecea, Oscar | |
dc.contributor.author | Martín, Vicente | |
dc.contributor.author | Ortega Calvo, M. | |
dc.contributor.author | Vázquez, Clotilde | |
dc.contributor.author | Pintó, Xavier | |
dc.contributor.author | Vidal, Josep | |
dc.contributor.author | Daimiel, Lidia | |
dc.contributor.author | Delgado Rodríguez, Miguel | |
dc.contributor.author | Matía Martín, Pilar | |
dc.contributor.author | Corella, Dolores | |
dc.contributor.author | Díaz López, Andrés | |
dc.contributor.author | Babio, Nancy | |
dc.contributor.author | Muñoz, Miguel Ángel | |
dc.contributor.author | Fitó, Montserrat | |
dc.contributor.author | García de la Hera, Manoli | |
dc.contributor.author | Abete, Itziar | |
dc.contributor.author | García Ríos, Antonio | |
dc.contributor.author | Ros, Emilio | |
dc.contributor.author | Ruíz Canela, Miguel | |
dc.contributor.author | Martínez González, Miguel Ángel | |
dc.contributor.author | Izquierdo, Marisol | |
dc.contributor.author | Serra Majem, Lluís | |
dc.date.accessioned | 2019-01-17T13:06:19Z | |
dc.date.available | 2019-01-17T13:06:19Z | |
dc.date.issued | 2018-12 | |
dc.identifier.citation | Nutrients 10(12) : (2018) // Article ID 2000 | es_ES |
dc.identifier.issn | 2072-6643 | |
dc.identifier.uri | http://hdl.handle.net/10810/30939 | |
dc.description.abstract | BACKGROUND: The aim of this analysis was to ascertain the type of relationship between fish and seafood consumption, omega-3 polyunsaturated fatty acids (omega-3 PUFA) intake, and depression prevalence.
METHODS: Cross-sectional analyses of the PREDIMED-Plus trial. Fish and seafood consumption and omega-3 PUFA intake were assessed through a validated food-frequency questionnaire. Self-reported life-time medical diagnosis of depression or use of antidepressants was considered as outcome. Depressive symptoms were collected by the Beck Depression Inventory-II. Logistic regression models were used to estimate the association between seafood products and omega-3 PUFA consumption and depression. Multiple linear regression models were fitted to assess the association between fish and long-chain (LC) omega-3 PUFA intake and depressive symptoms.
RESULTS: Out of 6587 participants, there were 1367 cases of depression. Total seafood consumption was not associated with depression. The odds ratios (ORs) (95% confidence intervals (CIs)) for the 2nd, 3rd, and 4th quintiles of consumption of fatty fish were 0.77 (0.63⁻0.94), 0.71 (0.58⁻0.87), and 0.78 (0.64⁻0.96), respectively, and p for trend = 0.759. Moderate intake of total LC omega-3 PUFA (approximately 0.5⁻1 g/day) was significantly associated with a lower prevalence of depression.
CONCLUSION: In our study, moderate fish and LC omega-3 PUFA intake, but not high intake, was associated with lower odds of depression suggesting a U-shaped relationship. | es_ES |
dc.description.sponsorship | This research was funded by the Spanish Ministry of Health (Carlos III Health Institute) through
the Fondo de Investigación para la Salud (FIS), which is co-funded by the European Regional Development
Fund (grant numbers and corresponding codes: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462,
PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14-00696,
PI14/01206, PI14/01919, PI14/00853), the European Research Council (Advanced Research Grant 2013–2018;
340918) grant to MAMG, the Recercaixa grant to J. S-S. and NB (2013ACUP00194), the grant from the Consejería de
Salud de la Junta de Andalucía (PI0458/2013; PS0358/2016), the SEMERGEN grant, and FEDER funds (CB06/03). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.subject | depression | es_ES |
dc.subject | docosahexaenoic acid | es_ES |
dc.subject | eicosapentaenoic acid | es_ES |
dc.subject | fish | es_ES |
dc.subject | omega-3 | |
dc.title | Seafood Consumption, Omega-3 Fatty Acids Intake, and Life-Time Prevalence of Depression in the PREDIMED-Plus Trial | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0). | es_ES |
dc.rights.holder | Atribución 3.0 España | * |
dc.relation.publisherversion | https://www.mdpi.com/2072-6643/10/12/2000 | es_ES |
dc.identifier.doi | 10.3390/nu10122000 | |
dc.departamentoes | Medicina | es_ES |
dc.departamentoeu | Medikuntza | es_ES |