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Fluorinated carbohydrates as chemical probes formolecular recognition studies. Current statusand perspectives

dc.contributor.authorLinclau, Bruno
dc.contributor.authorArdá, Ana ORCID
dc.contributor.authorReichardt, Niels Christian
dc.contributor.authorSollogoub, Matthieu
dc.contributor.authorUnione, Luca
dc.contributor.authorVincent, Stéphane P.
dc.contributor.authorJiménez Barbero, Jesús ORCID
dc.date.accessioned2020-10-16T12:35:59Z
dc.date.available2020-10-16T12:35:59Z
dc.date.issued2020-06-21
dc.identifier.citationChemical Society Reviews 49(12) : 3863-3888 (2020)es_ES
dc.identifier.issn0306-0012
dc.identifier.issn1460-4744
dc.identifier.urihttp://hdl.handle.net/10810/46950
dc.description.abstractThis review provides an extensive summary of the effects of carbohydrate fluorination with regard to changes in physical, chemical and biological properties with respect to regular saccharides. The specific structural, conformational, stability, reactivity and interaction features of fluorinated sugars are described, as well as their applications as probes and in chemical biology.es_ES
dc.description.sponsorshipB. L. thanks the EPSRC (EP/P019943/1) for funding. L. U. acknowledges funding from the postdoctoral fellowship from the Human Frontier Science Program Organization (HFSP) Grant No. LT000747/2018-C. N. C. R. acknowledges funding from Agencia Estatal de Investigacion (Spain) Grant No. CTQ2017-90039-R and RTC-2017-6126-1 and the Maria de Maeztu Units of Excellence Program. MDM-2017-0720. The group at Bilbao thank the Agencia Estatal de Investigacion of Spain (Grant RTI2018-094751-B-C21), the European Research Council (RECGLYCANMR, ERC AdG 788143), and the Severo Ochoa Excellence Accreditation SEV-2016-0644. SV acknowledges funding by FRS-FNRS (PDR grant number T.0102.18).es_ES
dc.language.isoenges_ES
dc.publisherRoyal Society of Chemistryes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/es/*
dc.subjectnuclear-magnetic-resonancees_ES
dc.subjectudp-galactopyranose mutasees_ES
dc.subjectmechanism-based inhibitorses_ES
dc.subjecthydrogen-bond acidityes_ES
dc.subjectchemoenzymatic synthesises_ES
dc.subjectenantioselective synthesises_ES
dc.subjectorganic fluorinees_ES
dc.subjectconformational behaviores_ES
dc.subjectaromatic interactionses_ES
dc.subjectmetabolic-inhibitorses_ES
dc.titleFluorinated carbohydrates as chemical probes formolecular recognition studies. Current statusand perspectiveses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.holderOpen Access Article. Published on 10 June 2020. Downloaded on 10/16/2020 11:18:03 AM. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licencees_ES
dc.rights.holderAtribución-NoComercial 3.0 España*
dc.relation.publisherversionhttps://pubs.rsc.org/en/content/articlelanding/2020/CS/C9CS00099B#!divAbstractes_ES
dc.identifier.doi10.1039/c9cs00099b
dc.departamentoesQuímica orgánica IIes_ES
dc.departamentoeuKimika organikoa IIes_ES


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Open Access Article. Published on 10 June 2020. Downloaded on 10/16/2020 11:18:03 AM. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence
Except where otherwise noted, this item's license is described as Open Access Article. Published on 10 June 2020. Downloaded on 10/16/2020 11:18:03 AM. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence