dc.contributor.author | Nasirimarekani, Vahid | |
dc.contributor.author | Strubing, Tobias | |
dc.contributor.author | Vilfan, Andrej | |
dc.contributor.author | Guido, Isabella | |
dc.date.accessioned | 2021-07-19T11:30:36Z | |
dc.date.available | 2021-07-19T11:30:36Z | |
dc.date.issued | 2021-07-06 | |
dc.identifier.citation | Langmuir 37(26) : 7919-7927 (2021) | es_ES |
dc.identifier.issn | 1520-5827 | |
dc.identifier.uri | http://hdl.handle.net/10810/52524 | |
dc.description.abstract | Suspensions of microtubules and nonadsorbing particles form thick and long bundles due to depletion forces. Such interactions act at the nanometer scale and define the structural and dynamical properties of the resulting networks. In this study, we analyze the depletion forces exerted by two types of nonadsorbing particles, namely, the polymer, poly(ethylene glycol) (PEG), and the block copolymer, Pluronic. We characterize their effects both in passive and active networks by adding motor proteins to the suspensions. By exploiting its bundling effect via entropic forces, we observed that PEG generates a network with thick structures showing a nematic order and larger mesh size. On the other hand, Pluronic builds up a much denser gel-like network without a recognizable mesh structure. This difference is also reflected in the network activity. PEG networks show moderate contraction in lateral directions while Pluronic networks exhibit faster and isotropic contraction. Interestingly, by mixing the two nonadsorbing polymers in different ratios, we observed that the system showed a behavior that exhibited properties of both agents, leading to a robust and fast responsive structure compared to the single-depletant networks. In conclusion, we show how passive osmotic compression modifies the distribution of biopolymers. Its combination with active motors results in a new active material with potential for nanotechnological applications. | es_ES |
dc.description.sponsorship | I.G. acknowledges support from the MaxSynBio Consortium, which is jointly funded by the Federal Ministry of Education and Research of Germany and the Max Planck Society. V.N. and I.G. acknowledge the European Union’s Horizon 2020 Research and Innovation Programme under the Marie Skłodowska-Curie grant agreement MAMI No. 766007. A.V. acknowledges support from the Slovenian Research Agency (grant no. P1-0099) | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | American Chemical Society | es_ES |
dc.relation | info:eu-repo/grantAgreement/EC/H2020/766007 | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.subject | microtubules | es_ES |
dc.subject | nonadsorbing particles | es_ES |
dc.subject | depletion forces | es_ES |
dc.subject | polymer | es_ES |
dc.subject | poly(ethylene glycol) | es_ES |
dc.subject | block copolymer | es_ES |
dc.subject | Pluronic | es_ES |
dc.title | Tuning the Properties of Active Microtubule Networks by Depletion Forces | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) | es_ES |
dc.rights.holder | Atribución 3.0 España | * |
dc.relation.publisherversion | https://pubs-acs-org.ehu.idm.oclc.org/doi/10.1021/acs.langmuir.1c00426 | es_ES |
dc.identifier.doi | 10.1021/acs.langmuir.1c00426 | |
dc.contributor.funder | European Commission | |
dc.departamentoes | Zoología y biología celular animal | es_ES |
dc.departamentoeu | Zoologia eta animalia zelulen biologia | es_ES |