dc.contributor.advisor | Shen, Bairong | |
dc.contributor.advisor | González Díaz, Humberto | |
dc.contributor.author | Chen, Li | |
dc.date | 2026-07-24 | |
dc.date.accessioned | 2025-01-27T14:49:47Z | |
dc.date.available | 2025-01-27T14:49:47Z | |
dc.date.issued | 2024-07-24 | |
dc.date.submitted | 2024-07-24 | |
dc.identifier.uri | http://hdl.handle.net/10810/71893 | |
dc.description | 388 p. | es_ES |
dc.description.abstract | In this doctoral thesis, I utilized FAERS data analysis methods to complete a neurotoxicity study on taxane drugs, a safety study on platinum drugs, and a cardiotoxicity study on ALK inhibitors. Additionally, I conducted a cost-effectiveness analysis to evaluate the economic value of gefitinib in Chinese patients with non-small cell lung cancer. Furthermore, I applied the IFPTML method to analyze safety and efficacy of the ovarian cancer treatments data in the hospital. This analysis led to the development of a prediction model, demonstrating the potential application of IFPTML in evaluating the safety and efficacy of a wider range of anti-tumor therapeutic drugs | es_ES |
dc.language.iso | eng | es_ES |
dc.rights | info:eu-repo/semantics/embargoedAccess | es_ES |
dc.subject | veterinary pharmacology | es_ES |
dc.title | From Classic Computational Studies To IFPTML Modelling Of Effectivity, Safety, Toxicity, And Cost Aspects In Different Cancer Therapies | es_ES |
dc.type | info:eu-repo/semantics/doctoralThesis | es_ES |
dc.rights.holder | © 2024 Li chen | |
dc.identifier.studentID | 988619 | es_ES |
dc.identifier.projectID | 23166 | es_ES |
dc.departamentoes | Farmacología | es_ES |
dc.departamentoeu | Farmakologia | es_ES |